If you’re a Cabinet official thinking of pursuing a new professional opportunity, Senate Republicans have a request: Now’s the time to call it quits.

The departure this week of Labor Secretary Lori Chavez-DeRemer, who is following former Homeland Security Secretary Kristi Noem and Attorney General Pam Bondi out the door, has some GOP lawmakers pondering a larger Cabinet shakeup and what that could mean to an unsettled Senate floor schedule.

Senate Republicans are already trying to juggle a shrinking window for lawmaking before the November midterms — including at least one potential party-line budget reconciliation bill, a litany of measures…

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